I'd like to disable the commenting function for all of my friends for some of my photos but not for all of them or my status updates which is the only privacy control panel I can find. Is this possible?
The Facebook privacy settings do not allow you to disable comments on a specific photo or album. You can exclude certain friends from commenting on (all) posts, which includes photos, but it will also keep them from commenting on status updates and other wall posts.
The closest you can get to what you want is to put all the "no comment" photos into one or more albums, then hide those albums from the people you don't want commenting on them. However, if you still want them to be able to see the photos, you're out of luck.