You can use a userscript to target the relevant input elements and apply your styling of choice. If you don't already have one, Tampermonkey is a very popular userscript manager.
Here's an example which you can configure:
// ==UserScript==
// @name GitHub: Monospaced textareas
// @version 1.0.0
// @description Set the textarea inputs on GitHub.com to use a monospaced font
// @license MIT
// @author Jesse Jackson
// @match https://github.com/*
// @namespace https://github.com/jsejcksn
// @noframes
// @run-at document-idle
// ==/UserScript==
(() => {
'use strict';
const styleElements = (querySelectorString, styleDeclarations) => {
const elements = document.querySelectorAll(querySelectorString);
elements.forEach(element => {
for (const declaration of styleDeclarations) {
element.style.setProperty(...declaration);
}
});
};
const styleDeclarations = [
['font-family', 'monospace'],
];
styleElements('textarea', styleDeclarations);
})();