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I cannot find a feature in Gmail which will let me set an auto-reply message sent each weekend automatically?!
So any person who send an email to me during Sat or Sun will get auto-reply that I will reply them on Monday.
Does such thing exist in Gmail?
In short, no you can't. You can use the 'automatic vacation' responder found on the first page of settings within GMail to set a specific date, however you're going to have to do that at the end of each week.
More here - http://support.google.com/mail/bin/answer.py?hl=en&answer=25922
