I just want to clean my Facebook news feed and start from crash adding my friends back.
What is the fastest way can I remove all friends from news feed?
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Officially, you have two possible courses of action:
Create a new account. Deleting your old one is not required, but would be recommended to prevent confusion.
Navigate to your friends list management page at
https://www.facebook.com/[your.username]/friends. Hover over the Friends box and then choose Unfriend. Repeat until your list is clear.
Unofficially, you could use a Greasemonkey script like this one.
Disclaimer: I have not used this myself and cannot verify its effectiveness.