Make a column from the Search button rather than from User.
Then, customize the search as follows: from:[user handle without @] -filter:replies
So, if I wanted every tweet by the @StackOverflow account without their replies, I'd set the following as the search term in my TweetDeck column:
It's because those GIFs are MP4s coded with high levels (6.0 etc.) that normal hardware can't play.
Disable "Hardware-accelerated video" decode in
(type this is address bar)
Keep "normal" hardware acceleration on!
Chrome > Settings > Advanced > System > Use hardware acceleration when
Take a note of their Twitter handle, go to Settings in Tweetdeck.
Within the Settings window, go to the Mute tab.
Under the Mute drop down select User. Then in the Using box, enter the users Twitter handle then press the Mute button.
In a recent update to Tweetdeck, you can also do it directly from a tweet.
Click their ...
Try HootSuite.com or bufferapp.com
These are pioneers for your sophisticated Social Media Management.
One of my friend is working on a similar concept, will share when it's ready. Till then try the above apps out. :-)
It's not possible in Tweetdeck from what I've seen. There was a website I used to use called Filttr (https://oauth.filttr.com/) that worked really well for filtering out tweets, and they did have functionality for blocking out replies.