Yes.
You can access your Gmail account as an IMAP account using an email client such as Thunderbird or MS Outlook and then use the client’s feature for deleting attachments.
Also you can automatically forward the messages to yourself and remove the attachment with Google's Docs. See http://techawakening.org/delete-attachments-from-gmail-without-deleting-the-emails/1842/Delete only Attachments in Gmail without Deleting the Emails using Google Docs