I had a huge data with blanks randomly set inside it, so using if(isblank())if(isblank())
was a bad idea for me as it would have been super labor intensive.
Instead, I downloaded my sheet as a csv, and opened it in TextWrangler (any text editor with find and replace will work). Then I found ',,' and replaced with ',0,'. I had to do that twice. Then when I reimported, I used if(isblank())if(isblank())
only on the first and last columns of my data set. Everything else was zeroed out. Only took about 5-10 mins.